The Best Hand Sanitizing Wipes with Alcohol in 2022 Reviews

Hand sanitizing wipes come in handy when water and soap can’t be easily accessed. The best part is that you can carry them with you almost anywhere. They come in small sizes that fit perfectly in pockets, handbags, purses, and diaper bags.

In comparison to the traditional water and soap, hand sanitizers have been found to be more effective in eliminating germs and keeping your hands cleaner for long. Some also contain emollients which help in keeping your hands moisturized and soft.

What constitutes an ideal pack of sanitizing wipes?


These wipes are meant to clean dust and dirt. As such, they need to be wet enough for this purpose. However, some come overly wet making them uncomfortable to use.


For hygienic purpose, opt for a package with individually wrapped wipes. This helps in maintaining their moisture for long.


Single sealed hand wipes are always easy to stuff in pockets or purses. If you need more, then the package should easily fit in your travel bag and also be easily accessible. Pop-up canisters are stylish and convenient for on-the-road use.

Fragrance or no fragrance

These wipes come either scented or scent-free.

10. Eo Hand Sanitizer Wipes, 24 count

  • By: EO
  • Item Weight: 5.1 ounces
  • Product Dimensions: 3.6 x 4.9 x 2.6 inches 

EO is a big name in antiseptic and other healthy living products. Their hand wipes are amongst the most sought-after, of course, for several reasons. Firstly, they come scented with a sweet lavender fragrance with a fresh and herbal touch.

Secondly, each package holds 24 wipes separately wrapped. This makes it easy to stuff some into your pockets, handbag, or purse for on-road use. Again, you’ll be able to pack some for your children for use when they can’t find water.

In addition, EO hand wipes hold a good amount of moisture. Each wipe also does a lot of cleaning on surfaces without causing any damage.


  • Have a fresh lavender scent.
  • Are soft on hands and surfaces too.


  • The smell is strong and may disturb some people.

9. Purell 9121-03-EC Hand Sanitizing Wipes

  • By: Purell 
  • Item Weight: 9.1 ounces
  • Product Dimensions: 21.4 x 11.9 x 7.7 inches 

Purell offers one of the most gentle, convenient, and priceless ways of maintaining our hygiene. Their sanitizing wipes come packed in easy-to-use canisters. The package also features 3 different scents. Each package has 1 fragrance-free container, another one with fresh citrus scent, and yet another one with a clean, refreshing scent.

PURELL Hand Sanitizing Wipes Variety Pack, Clean Refreshing Scent and Fragrance Free, 40 Count Sanitizing Wipes Canisters (Case of 3) - 9121-03-EC
  • WET WIPES: Pre-moistened hand wipes that are easy and convenient to use at home, work or on-the-go
  • GERM KILLER: Sanitizing wipes that safely clean your hands, killing 99.99 percent of illness causing germs
  • TRUSTED BRAND: Purell is the most trusted and used hand sanitizer by hospitals and clinically proven effective in maintaining skin health
  • PORTABLE TRAVEL WIPES: Small canister that easily fits in a car cup holder to safely clean hands when soap and water are not available
  • SAFE AND GENTLE: Wipes without harsh chemicals that are safe and gentle on skin

Each canister holds 40 wipes. Again, they fit perfectly in most car cup holders and can also fit in handbags, backpacks, and purses for on-the-go use. Moreover, these wipes have been dermatologist tested and found to kill 99.99% of all germs. They are also alcohol-free and don’t contain harsh chemicals.


  • Come in canisters for easy portability.
  • Are alcohol-free.


  • The feeding opening is quite small.

8. Lysol Disinfecting Wipes (6 Packs of 110 Wipes)

  • By: Lysol Disinfecting Wipes
  • Item Weight: 14.6 pounds
  • Product Dimensions: 15 x 10 x 8.4 inches

Lysol comes in 6 packs each carrying 110 wipes. At a little over 30 bucks, this package has the best bang for your bucks. In case you need reliable wipes that can be used all around the home, these are yours.

Lysol - 78849CT 19200788496 Disinfecting Wipes, Lemon & Lime Blossom, 660ct (6X110ct), Packaging May Vary White
  • Lysol is stronger than the competition (vs. leading competitor – based on lab results)
  • Disinfects & kills Kills 99.9% of viruses & bacteria, including 8 cold & flu viruses when used as directed
  • Unique Micro-Pocket Pattern ideal to quickly trap & lift everyday messes
  • Removes allergens. To disinfect - Allow to remain wet for 4 minutes. Allow surface to air dry. Toss dirty wipe away. To sanitize -Allow to remain wet for 10 seconds. To sanitize / disinfect - Pre-clean surface. Use enough fresh wipes to thoroughly wet surface
  • Safe to use on electronics: Smartphones, Tablets & Remote Controls

They are versatile sheets with lemon and lime extracts which help in eliminating 99.99% of germs. They are not only perfect for sanitizing your hands and face but also for kitchen use and furniture. Again, they come in a pop-up container for easy opening and travel.


  • Are ideal for grime.
  • Have value for money.


  • Some users find them too wet.

7. Cleanwell Natural Hand Sanitizing Wipes (8 packs)

  • By: Cleanwell 
  • Item Weight: 1 ounces
  • Product Dimensions: 2.8 x 0.8 x 5.2 inches

These Cleanwell Natural Hand Sanitizing Wipes come in packs of 10. The packages are resealable which helps in maintaining the moisture of the unused wipes. Again, the packs are easy to carry in your pockets and purse.

Its users appreciate the fact that the wipes are alcohol-free and don’t have any added colors. Consequently, they are safe for kids and sensitive skin. Cleanwell Hand Wipes also have a light thyme oil fragrance that isn’t overpowering at all.


  • They are alcohol-free.
  • Have a unique light scent.


  • They are extremely wet.

6. Sani-Hands Hand Sanitizer Wipes

  • By: Sani Hands
  • Item Weight: N/A
  • Product Dimensions: N/A

These wipes by Sani Hands are amongst the most highly rated on this list. They come in a box with 100 pieces. Each wipe measures 5’’ by 7.75’’ which is enough to sanitize both hands. On this note too, each piece is wrapped separately. Therefore, each wipe holds its original wetness for long. This packaging also makes it easy to use on the go.

Sani-Hands Hand Sanitizer Wipes 100 Packets Per Box
  • 100 SaniHands Wipes in handy zip lock bag
  • Handy size is 5" x 7.75" paper style wipe, like you would get at rib place!
  • Cleans and moisturizes excellent for adults and kids on the go
  • Kills 99.99% of germs that can make you sick - antimicrobial
  • Removes soil and bacteria more effectively than gels alone

They are hospital proven to eliminate 99.99% of all the disease causing germs. These wipes also pack loads of Aloe Vera extracts and Vitamin E that help in softening your hands. The sheets’ size and design also make removing soil quite fast and effective than their gel competitors. Lastly, they are fragrance-free!


  • They are fragrance-free.
  • Each wipe has a handy size.


  • They use alcohol.

5. Natural Sanitizing Wipes

  • By: Cleanwell
  • Item Weight: 8.5 ounces
  • Product Dimensions: 3.3 x 3.3 x 6.6 inches 

These wipes come in a compact pop-up canister. There are 40 wipes in total. This pack is, therefore, ideal if you need some wipes for a trip or flight. They are alcohol-free and use oregano oil which is a well-known disinfectant. They also have a fresh orange vanilla scent.

CleanWell 40 Count Orange Vanilla Hand Sanitizer Wipes - Discontinued as of June 22, 2020
  • COMPARE WITH: Dr. Bronner's, EO, Everyone, Purell, Babyganics, and Wet Ones.

On the downside, some may find the smell somehow pungent. It may also cause a little irritation if it comes in contact with the eyes.


  • Use oregano oil disinfectant.
  • Come in presentable package.


  • The scent may be pungent.

4. Germ-X Hand Sanitizing Wipes (with alcohol)

  • By: Germ-X
  • Item Weight: 1 pounds
  • Product Dimensions: 10 x 6 x 4 inches 

Are you looking for professional-grade premium wipes for use at home, in airplanes, in restaurants, camps, and hotel rooms? Here you go. Past users are hoping that these wipes will never be discontinued.

This pack by Germ-X holds 100 sanitizing wipes. Each of the towelettes measures 6’’ by 8’’. They are doubtlessly the largest in size.

The wipes come individually sealed for hygiene, convenience, and to prevent them from drying out. Without forgetting, these wet wipes feature Aloe Vera and Vitamin E. As such, your hands remain moisturized and soft even with repeated use.


  • Kills 99.99% germs.
  • Each wipe is separately sealed.
  • Has aloe and vitamin E.


  • No adverse flaw has been reported.

3. Babyganics Hand Sanitizing Wipes (Alcohol-Free)

  • By: Babyganics
  • Item Weight: 4 ounces
  • Product Dimensions: 6 x 5 x 4 inches 

As your kids continue with their non-stop explorations, it’s a good idea to have these wipes ready for them. They have been designed specially for your child’s sensitive skin.

Babyganics Alcohol-Free Hand Sanitizer Wipes, Mandarin, 20 ct, 4 Pack, Packaging May Vary
  • Made without parabens, sulfates, phthalates, synthetic fragrances or dyes
  • Moisturizing
  • Alcohol-free
  • Kills 99.9% of common bacteria
  • Non-allergenic

As such, they don’t have alcohol or other allergenic ingredients that may cause irritation. Most importantly, they are Pediatrician and Dermatologist proven to be safe. They also have a fresh citrus scent. They also clean without leaving that sticky feeling behind.


  • Are alcohol-free.
  • Don’t leave sticky feeling.


  • They dry out fast.

2. Wet Ones Hand and Face Wipes

  • By: Wet Ones
  • Item Weight: 4.8 ounces
  • Product Dimensions: 4.8 x 2.8 x 3.1 inches 

A package of these antibacterial hand and face wipes contains 5 packs each with 24 sheets. Each wipe is singly wrapped for convenience and easy portability. You can have several of them in your car, office locker, handbag, backpack, and also sneak some in your kids’ school bags for use while away.

Wet Ones Wet-4721 Antibacterial Hand and Face Wipes Singles, 24-Count (Pack of 5)
  • Antibacterial formula
  • Kills 99.99 Percent of Germs
  • Hypoallergenic and enriched with skin conditioning aloe.Paraben free.Does not leave skin dry or sticky
  • Perfect for quick clean UPS of dirt and messes
  • Portable and convenient

Wet Ones wipes are alcohol-free and hypo-allergenic. They also boast skin-conditioning aloe which helps in keeping your hands smooth and moisturized. Each wipe measures 4.8 x 2.8 x 3.1 inches and is adequately moisturized to make cleaning and dusting more than a breeze.


  • They are large.
  • They are wet enough.


  • They are scented.

1. Huggies Natural Care Baby Wipes

  • By: Huggies
  • Item Weight: N/A
  • Product Dimensions: 7.9 x 12.8 x 9.4 inches

As we hunt for hand sanitizers, we can’t forget that what works for us may not automatically be safe for the little ones. Therefore, we need to order a special package for them.

HUGGIES Natural Care Unscented Baby Wipes, Sensitive, 3 Refill Packs, 552 Count Total
  • Huggies Natural Care baby wipes are softer for sensitive skin
  • Our simplest formula yet for a gentle clean — 99% water with aloe and vitamin E
  • Fragrance Free baby wipes are dermatologically tested and hypoallergenic – MI-free, paraben-free and alcohol-free
  • Soft, Triple Clean* Layers are thick enough to handle any mess
  • Huggies Natural Care Refill Packs have a resalable closure to help keep your baby wipes fresh and moist

We can’t look any further than what Huggies have for them. These are fragrance-free and conveniently wet wipes. They are soft on your toddler’s hands and body. In addition, they are thick and sturdy enough to handle different messes fast and easily. Even better, they come in a compact, strong, and refillable pack that fits well in your diaper’s bag. They also have aloe extracts and vitamin E ideal for your baby’s moisturized and glowing skin.


  • They are fragrance-free.
  • Safe for toddlers.


  • Some find them overly wet.

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